At least five people have been killed after a suspected US drone fired missiles at a village in north-west Pakistan, local officials said.
The officials said missiles hit the village of Baghar in South Waziristan, close to the Afghan border.
The missiles are reported to have struck a militant training camp.
The attack comes as the top US military commander met Pakistani officials to discuss increasing tensions over US attacks along the border.
At least six people were injured in the attack, said a BBC correspondent in the region.
A Pakistani army spokesman said the military was investigating reports about the incident.
'Ground violations'
Also on Wednesday, US Adm Michael Mullen met Pakistani Prime Minister Yousuf Raza Gilani to discuss US operations along the troubled border with Afghanistan.
The men discussed "measures to defuse tension between the two countries, following a spate of air and ground violations along the Pakistan-Afghan border", the state news agency APP said.
The tribal region of South Waziristan is one of the main areas from which Islamist militants launch attacks into Afghanistan.
Last week, it emerged that President George Bush had authorised cross-border attacks by US troops based in Afghanistan.
The Pakistan army has said that they will not tolerate such incursions.

Source BBC