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Old Thursday, June 19, 2014
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Quote:
Originally Posted by Maidah shaikh View Post
Does anybody know the answer of this question ?


Explain how DNA , mRNA and Proteins are inter related to each other ?

Transcription:
The process to make RNA from DNA. This process occurs in the nucleus of the cell. In simple terms: RNA polymerase binds to the DNA and transcribes a pre-mRNA strand, which contians coding regions (exons) and non-coding regions (introns). The pre-mRNA is made mature by removing the intron regions (non-coding regions) and adding a 5'Guanosine cap and a 3' poly A tail (A=Adenosine). This is called a mature mRNA. All of this occurs in the nucleus.


Translation:
This process translates mRNA to proteins. mature mRNA leaves the nucleus and goes to a ribosome (the ribosome (aka rRNA) binds to the region before the start codon. In bacteria, it is called
the shine-delgarno sequence). Then tRNA comes into the p-site in the ribosome and you have base pairing between the mRNA and
tRNA. Once this interaction occurs, it causes a conformational change within the tRNA and that releases the amino acid. The amino acids string together to make a protein.
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aghaadnan (Tuesday, July 22, 2014), Maidah shaikh (Thursday, June 19, 2014)